The Colorado Buffaloes and Houston Cougars play on Friday, Sept. 12, at TDECU Stadium in Houston in a game on the college football Week 3 schedule.
Which team will win the college football Week 3 game?
Check out these college football Week 3 picks and college football Week 3 predictions for the Big 12 game, which can be seen at 4:30 p.m. MST on ESPN (stream with FUBO).
Houston is a 5.5-point favorite over Colorado in college football Week 3 odds for the game, according to BetMGM Sportsbook.
The Cougars are -220 on the moneyline, while the Buffaloes are +180. The over/under (point total) for the game is set at 43.5 points.
College football Week 3 picks: Clemson vs Georgia Tech | Wisconsin vs Alabama | Georgia vs Tennessee | Florida vs LSU | Texas A&M vs Notre Dame | South Florida vs Miami | Pittsburgh vs West Virginia | Kansas State vs Arizona | Colorado vs Houston | Oregon State vs Texas Tech | NC State vs Wake Forest | Vanderbilt vs South Carolina | Arkansas vs Ole Miss | USC vs Purdue | Oregon vs Northwestern | UTEP vs Texas | Ohio vs Ohio State | Central Michigan vs Michigan | Iowa State vs Arkansas State | Abilene Christian vs TCU | Texas State vs Arizona State | Utah vs Wyoming | The Republic’s Big 12 score predictions
Jeremy Cluff writes: “Coach Prime comes to Houston without Shedeur Sanders, Travis Hunter and others, but the Buffaloes still have some firepower, particularly on offense.”
It writes: “After extensive simulations, our model gives Colorado a win probability of 37%, while Houston has a win probability of 63%.”
The site gives the Buffaloes a 42.1% shot at winning the college football Week 3 game against the Cougars on Sept. 12.
Bill Speros writes: “Coach Prime and the Buffs have shown signs of life in the Post-Shedeur-Travis Hunter Era. The Cougs begin their Big 12 schedule with test on the road. The Buffs find enough holes in Houston’s defense to grab the road win.”
The site’s formula predicts that the Buffaloes will defeat the Cougars in the Big 12 Conference Week 3 college football game.
Big 12 football game picks: Arizona | Arizona State | Baylor | BYU | Cincinnati | Colorado | Houston | Iowa State | Kansas | Kansas State | Oklahoma State | TCU | Texas Tech | UCF | Utah | West Virginia | Projected Big 12 standings, records
Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on X, formerly Twitter @Jeremy_Cluff.
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